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HIGH FRUCTOSE AND OPIOIDS ADDITION POSSIBILITY?

Diets high in high fructose corn syrup may indirectly contribute to opioid dependence, according to research presented this week at Neuroscience 2017, the annual meeting of the Society for Neuroscience.

Previous research has shown that high fructose corn syrup (HFCS) impacts the brain in a way similar to addictive drugs. It triggers a “reward response” in the brain’s reward circuitry that leads to continued cravings, in much the same way as a narcotic. These similarities have led researchers to wonder whether diets high in HFCS may play a role in opioid dependence.

In the latest study, rats were fed a diet high in HFCS before being given a dose of oxycodone, one of the prescription pain killers at the center of the opioid epidemic. Researchers then examined the rats’ behavior and changes in how their brains responded to the drug.

The results showed that the brains of rats given HFCS produced lower levels of dopamine—the neurotransmitter that fuels the brain’s reward circuitry—when given their dose of oxycodone. This suggests that HFCS decreased the reward response in the rats’ brains – in other words, it tuned down the explosion of dopamine that would normally accompany taking oxy.

The rats’ behavior also changed. Taking oxy usually results in certain exaggerated changes in “locomotive behavior,” but that behavior was also reduced in rats given HFCS.

“Our experiments show that chronic pre-exposure to high-fructose corn syrup impacted both the neural and behavioral responses to oxycodone, resulting in changes likely to impact drug-taking and drug-seeking behavior,” said co-lead author Meenu Minhas, a PhD student at the University of Guelph in Ontario, Canada.

For people taking prescription opioids, the takeaway here is that your diet may influence how much of the drugs you find yourself wanting to take. A diet high in HFCS (and possibly sugar in general) could be dampening your brain’s response to the drugs, which leads to taking more to get the same effect.

“These results suggest that nutrition, and sugar intake in particular, can influence some responses to opioids, a finding that may be relevant both to clinical uses of opioids and to treating addiction,” added Minhas.

The research findings were presented at Neuroscience 2017.

Are Energy Drinks BAD for You?

Few people would ever claim that energy drinks are healthy, but it’s easy to assume they’re fine for your health given how popular they are. But new research suggests they’re actually pretty bad for you.

The study, published in Frontiers in Public Health, reviewed current scientific evidence on energy drinks and found that their short-term benefits (namely, they can make you feel more awake) are outweighed by scary health risks like mental health problems, risk-seeking behavior, increased blood pressure, obesity, tooth erosion, and kidney damage.

The study’s researchers argue that there is a need for more regulatory oversight in the energy drink market, including caffeine limits, restricted sales, and regulations on marketing strategies, which are often targeted at kids and teens.

While each energy drink is slightly different, most contain water, sugar, caffeine, vitamins, and stimulants like guarana, taurine, and ginseng. They can have up to 100 milligrams of caffeine per ounce, which far exceeds the recommended daily limit of 400 milligrams for adults. (An 8-ounce cup of coffee, by comparison, contains 95 milligrams of caffeine for the entire cup.)

That’s pretty concerning. “The excess caffeine may contribute to cardiovascular outcomes, such as increased blood pressure,” study co-author Josiemer Mattei, an assistant professor of nutrition at the Harvard T.H. Chan School of Public Health, tells Yahoo Lifestyle. While caffeine may have some beneficial effects when you have it in moderation, at high doses it can impact your cardiovascular system, she says. “The caffeine amount at which these symptoms may occur is lower for children and adolescents than for adults, making the high content of caffeine in energy drinks so concerning for younger age groups,” Mattei says.

The sugar in energy drinks isn’t great either. It can increase a person’s risk of obesity, high blood sugar, and dental cavities, she points out. There are also plenty of other ingredients in the drinks that there isn’t a lot of scientific information about, which is concerning.

Moreover, it’s hard to know what, exactly, is in your energy drink. “A lot of these have ingredients in them that aren’t on the label,” David Cutler, MD, a family medicine physician at Providence Saint John’s Health Center in Santa Monica, Calif., tells Yahoo Lifestyle.

Energy drink companies can get away with this because their product is considered a supplement by the Food and Drug Administration and isn’t closely regulated, Beth Warren,  founder of Beth Warren Nutrition and author of Living a Real Life With Real Food, tells Yahoo Lifestyle. “Therefore, consuming energy drinks can be potentially harmful, or their affects are unknown,” she says. That’s why she recommends that people be “highly cautious” of drinking these.

Ultimately, “the long-term negative health effects of consuming energy drinks outweigh any potential short-term benefit,” Mattei says. Cutler agrees. “It’s best to avoid them altogether,” he says.

 

Why does my vending machine leak water? What should I do?

Everyone wants to ensure that their machine vends cold beverages, especially during the warm summer months. In high humidity areas, you may find some condensation building up on your vending machine. This can happen even if it is located in an air-conditioned building. You may see water leaking out from under your vending machine. We would like to offer you some ideas to check if your machine is having an issue with excess condensation and some solutions to help you fix the problem.

The primary causes of excess condensation are:
1. An air leak from a damaged door gasket
2. A loose door
3. A worn-out T-handle or missing parts
4. Missing or broken delivery flap
5. Mis-aligned door or Mis-aligned inner door
6. Low airflow from the fan or a very high humidity environment
7. A compressor issue
The compressor issues can range from low freon causing excess frost on the evaporator to a short cycling thermostat that doesn’t stay turned off for more than a minute or two which can cause excess condensation.

One thing you should check is if you have over-tightened the door. Over tightening the beverage compartment door can damage the seal used to keep the warm air out and the cold air in. These small gaps will create a mixture of warm and cool air to combine and can possibly produce condensation.

To prevent this, turn the locking handle until the gasket around the door is flush. Then turn the handle another half a turn to secure the connection to ensure you do not over-tighten the door.

You’ll want to check for any gaps in the inner door as well. Look at the inner door and make sure the lower edge of the gasket isn’t sagging below the door. Make sure that it fits snugly and that there are no places where the cooled air can escape.

Another thing to check is for any leakage of water into the machine or below the machine from the drip pan. This can be remedied by adding a sponge to the drip pan to help it hold more fluid, and evaporate. You could also place an inexpensive baking dish or tray below the vending machine to catch any water that may escape.

Once you have checked a few of these things, get a thermometer and put it inside the machine drink compartment so you can confirm the temperature. You are looking for approximately 38 – 43 degrees Fahrenheit. You want to feel inside and see if you can feel the air flow and vibration of the fans. If you can feel the air flow but it’s not getting cold, you may have an issue with the fans. Many problems that you are having with your cooling deck require a specialized technician to troubleshoot. A technician should be called to work on this area of your machine.

You may also want to check where the cooling line enters the tray and if there are any gaps you can seal those with plumber’s putty. A small hole could be drilled for an additional drainage line if your collection pan is not big enough to hold the excess condensation. That way it can drain down in to a pan placed under the machine.

Lastly, cleaning the condenser coil is vital to the lasting success of a vending machine, which along with a few precautions can insure that your machine vends cold product consistently. When placing a vending machine, it is important to make sure that the vending machine is located at least 4-6 inches away from the wall to assure proper ventilation for units that have a refrigeration system. It is recommended to clean it at least once a year, and possibly up to once every couple of months depending on the location. A factory location will naturally have more debris in the air than an office setting, and therefore require more attention. A small vacuum, a rag, or a can of compressed air will go a long way to insure that your vending machine goes the distance.

Every machine is different and you will want to check the owner’s manual for your machine. The manual should have information about how to set the temperature in your machine. It may also have a diagram to help you see the inner workings of the cooling deck. It may offer some troubleshooting techniques you can try. It’s always a good idea to go to your manual first when you have any issue with your machine

Understanding shipping services

Lift gate Pickup and Delivery
If you don’t have a dock, you may need to schedule a lift gate to load your freight shipment onto the truck. If the freight receiver doesn’t have a dock, a lift gate will be necessary to unload the shipment. Schedule lift gate pickup and delivery when getting a quote to avoid delays and additional charges.
Inside Pickup and Delivery
If your freight needs to be picked up or delivered to the inside of a business or commercial location rather than a receiving area, there may be an additional charge.
Residential/ Non-commercial
If you are picking up or delivering a shipment to a residential area, most carriers charge an extra fee. Depending on the carrier, fees may be applied to residential homes, farms, ranches, or businesses located within a residential area.
Reweigh and Inspection Fees
Carriers routinely inspect shipments to ensure the proper weight and class information is listed on the BOL. If the weight increases and/or class of your shipment is incorrectly listed on the BOL, the carrier will make the correction and weight and inspection fees will be assessed in addition to any extra shipping charges.
Limited Access
Freight pickups or deliveries to locations that have limited or secured access such as prisons, schools, churches, airports and construction areas will require an additional fee.

In addition, some fees are incurred when your shipping plans or schedule changes. Ensure that your shipments are ready for pickup and delivery as scheduled and you can avoid or reduce these common penalty charges.
Re delivery
If nobody is available to accept a delivery, or if the delivery is changed to a new location, a re delivery fee will be applied.
Vehicle Not Used
If your shipment is not ready when the driver arrives for a scheduled pickup, you will be charged a fee. Avoid this fee by canceling or rescheduling pickups before the driver is deployed.

 

ALL KINDS OF VENDING MACHINES

(CNN)
From diapers to needles to bike helmets, vending machines have been rebuilt to go beyond breath mints and cold soda.

These automated dispensers have come a long way since their invention in the early 1800s. Although snacks and drinks remain the most common items you’ll find being dispensed, some are focusing on health, safety, and medical items.
Here are a few you’ll find around the world.

Baby essentials, Long Island, New York

Even the most well-organized parents can’t plan for everything. WeGoBabies founder Vanessa Carrington found that out the hard way when her family got stuck in an airport and ran out of supplies.
Now, with a few taps on the LED screen and a credit card swipe, users of the machine she created can unlock access to items as small as a packet of baby formula or as big as a travel booster seat, all available 24/7. The first machine is scheduled to open in May at the Broadway Mall in Long Island, New York.
The creators of the high-tech machine hope to save parents some time by replacing off a frantic trip to a convenience store with a visit to a vending machine stocked with the essentials — before a baby meltdown.

Nursing supplies, Baltimore

For breastfeeding mothers, returning to work often means toting around a breast pump. The devices require tubes, valves, storage containers and a number of small pieces that can easily be forgotten.
A machine at Johns Hopkins Hospital in Baltimore aims to support these breastfeeding moms. Vending machines in the employee lactation room sell nursing pump accessories, storage bottles, breast pads, nipple cream and other supplies.

Cycling helmets, Melbourne, Australia

Whether for exercise or sightseeing, locals and tourists alike populate Aussie roads, but local law requires that all cyclists keep their craniums covered.
If you find yourself wanting to take a spin near Southern Cross Station in Melbourne but forget your gear, just look for the vending machine run by the local bike share. For $5, you can select your helmet size and get a new blue helmet.

Prescription medications, various locations

If you don’t want to run to the store or you just can’t make it to the pharmacy during business hours, InstyMeds machines might have you covered.
Although the machine does not support refrigerated medications, virtually any other prescription can be distributed. As it’s accessible 24 hours a day, seven days a week, the creators of the 1,500-pound secure automated pharmacy hope to provide a private and convenient option for patients to receive their medications.
After leaving a health care provider, consumers can use an identification number to receive their medication. The machine is linked to a secure electronic health database and monitored around the clock. The machines are in more than 200 locations in the US and abroad, including college campuses, emergency rooms, doctors offices, corporate and student wellness centers.

Condoms, tampons and more, University of California, Davis

On campus at the University of California, Davis, Activities and Recreation Center, students can find a vending machine that dispenses items such as condoms, tampons, pregnancy tests, Advil and the morning-after pill, or Plan B. It’s called the “Wellness To Go” Machine.

China's lack of sex education is putting millions of young people at risk

China’s lack of sex education is putting millions of young people at risk
The machine’s debut came after students spent two years working with staff at the university’s student health and counseling center to make sexual health products readily available. Items are accessible whenever the building is open, from 5 a.m. to 1 a.m. The vending machine offers an additional option for supplies such as contraception, which are also available at the student health center.

Needle exchanges, Las Vegas

Harm-reduction advocates have turned to vending machines to make clean supplies readily available for people who use injectable drugs.

Canada's safe injection center brings drug addicts 'out of the alleys'

Canada’s safe injection center brings drug addicts ‘out of the alleys’
Needle exchanges are not aimed at reducing the number of users, but advocates hope that providing clean needles will reduce the spread of diseases, such as HIV and hepatitis C, that can be contracted when people share needles.
At the Community Counseling Center of Southern Nevada, clean needle kits including syringes, alcohol swabs, a tourniquet and a disposal container for used syringes are offered free of charge. The machine is in a drug treatment center, and those who wish to have access must first register with Trac-B Exchange to sign up. The process does not involve any notification of law enforcement or a requirement to enter treatment.

First-aid supplies, coming to theme parks

The machines are still in development, but soon, visitors to some Six Flags theme parks won’t have to look far for first-aid supplies after an accident. RecMed, a vending machine company started by middle-school student Taylor Rosenthal, will offer consumers a quick option.
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Users can buy prepackaged first-aid kits for dealing with issues such as sunburns, cuts, blisters and bee stings, ranging in price from $5.99 to $15.95. Individual supplies like bandages, rubber gloves, hydrocortisone wipes and gauze pads are also for sale from $6 to $20.

Toilet paper, Mexico

In Mexico and many other countries, individually wrapped toilet paper rolls can be purchased at over 6,000 vending machine locations. Prices at the Mexican machines range from 20 to 100 pesos, or about $1 to $5.
Around the world, these machines, such as the Teggra dispenser, are popular enough that some ad agencies have put clients’ information on roll packaging. These two-ply tellers can be found at gas stations, bus terminals and shopping malls to help on those occasions when the stalls aren’t stocked.

CNN’s Alvaro Pichardo contributed to this report.

Contact Us

Piranha, LLC
50601 Central Industrial Drive
Shelby Township, Michigan 48315, USA

Email: info@piranhavending.com

Phone: 800-764-8245 * 586-997-1212

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HIGH FRUCTOSE AND OPIOIDS ADDITION POSSIBILITY?

Diets high in high fructose corn syrup may indirectly contribute to opioid dependence, according to research presented this week at Neuroscience 2017, the annual meeting of the Society for Neuroscience. Previous research has shown that high fructose corn syrup (HFCS) impacts the brain in a way similar to addictive drugs. It triggers a “reward response” […]

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